For any tissue or body cell to repair and
heal- proteins are needed. Amino acids (proline, glycine, lysine, etc) the
building blocks for proteins are extremely crucial for cell function and
repair. For repairing the cell wall fatty acids are needed. Carbohydrates are
needed to provide energy for the regular metabolic processes that take place. High protein and high calorie diets can be tailored and provided by the nutritionist to enhance the wound healing. Vitamins
and minerals play a great role in many chemical reactions that occur during
various body metabolic processes and in wound healing.
For example,
Vitamin A (retinoic acid) – important for collagen production and epithelisation (surface cell growth).
Vitamin E (alpha tocopherol) – antioxidant that destroys free radicals and helps healing.
Vitamin C (ascorbic acid) – Helps collagen formation
Iron, copper – helps collagen formation.
Zinc- zinc is a constituent of many enzymes treated for wound healing as well as it is a potent antioxidant.
For example,
Vitamin A (retinoic acid) – important for collagen production and epithelisation (surface cell growth).
Vitamin E (alpha tocopherol) – antioxidant that destroys free radicals and helps healing.
Vitamin C (ascorbic acid) – Helps collagen formation
Iron, copper – helps collagen formation.
Zinc- zinc is a constituent of many enzymes treated for wound healing as well as it is a potent antioxidant.
Antioxidants usually are reducing agents and examples include: superoxide
dismutase, catalase, peroxidasesglutathione,
vitamin C, vitamin A, vitamin E etc. Antioxidants are substances that inhibit
the oxidation process induced by other substances. Oxidation reactions can be
detrimental at the cellular level since they can produce free radicals which
can damage the cell and lead to cell death. Antioxidants stop these processes
by removing the free radicals. Antioxidants can help the healing processes that
are required to heal complex wounds.
If the patient has anemia (low hemoglobin),
this will affect the oxygen carrying capacity of blood and the wound will get
less oxygen resulting in poor healing. Albumin is another protein in the blood
that is important for wound healing. Low levels of albumin can be
detrimental to the wound healing process and should be corrected.
In a patient with a non healing wound
these factors need to be treated aggressively as they all contribute to non-
healing.
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