we often come across some wounds that fail to
heal. There are number of factors that hamper the normal wound healing process.
It is important for us to recognize this so that we can address the problem.
A large number of patients go around from
doctor to doctor with chronic nonhealing wound though their diabetes and
other contributing factors are corrected. A look at this wound may show
dead and devitalized tissue (slough, necrotic tissue) that releases endotoxins,
which hamper the healing process (decreases epithelisation and fibroblast
activity). Further a large number of traumatic wounds have some foreign
bodies- like sand, dirt, glass pieces and others that get embedded within the wound
during the accident. The presence of foreign bodies in the wound has been
scientifically shown to increase the incidence of wound infection- which
again hampers wound healing as we have already seen. Therefore it is logical
that all the dead tissue and foreign bodies must be removed from the wound
to help the healing process. Sometimes the cause of a non healing wound
is an underlying bony infection (osteomyelitis) or infected fracture site that
is constant discharging material (pus, serous fluid) that prevents the
overlying wound from healing.
In all these cases the body can do nothing to
heal the wound and needs external aid. A surgeon will debride (remove
all dead tissue) and clean up the wound using his knife. He will manage
the underlying bone problem and treat the bone infection or the dead bone which
prevents the wound from healing. If the blood flow to the limb or wound
area is decreased or stopped due to diseased blood vessels, one has to evaluate
(Doppler study / angiogram- will help to find if the blood vessels are patent
and functioning) and repair these blood vessels to increase the blood flow
(angioplasty or arterial bypass grafting) thereby removing the blockage and
increasing the lumen of blood vessels or replacing the damaged or blocked blood
vessels by a new blood vessel from the person’s own body or by using an
artificial graft. The same is true for peripheral vascular diseases of the
blood vessels that result in the poor blood supply to the wound.
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